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Phenotype analysis of peripheral blood lymphocytes and matched tumor infiltrating lymphocytes form CRC patients. A Typical results of flow cytometry analysis revealed the frequency of <t>CD39</t> + CD103 + CD8 + T cells in PBLs and matched TILs of CRC patients. B Statistical analysis of the frequency of CD39 + CD103 + T cells in PBLs and matched TILs of CRC patients. C Typical results of the frequency of CD8 + PD-1 + T cells in PBL and matched TILs of CRC patients. D Statistical analysis of the frequency of CD8 + PD-1 + T cells in PBLs and matched TILs of CRC patients. E Typical results of the frequency of CD8 + CXCL13 + T cells in PBLs and matched TILs of CRC patients. F. Statistical analysis of the frequency of CD8 + CXCL13 + T cells in PBLs and matched TILs of CRC patients
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Phenotype analysis of peripheral blood lymphocytes and matched tumor infiltrating lymphocytes form CRC patients. A Typical results of flow cytometry analysis revealed the frequency of <t>CD39</t> + CD103 + CD8 + T cells in PBLs and matched TILs of CRC patients. B Statistical analysis of the frequency of CD39 + CD103 + T cells in PBLs and matched TILs of CRC patients. C Typical results of the frequency of CD8 + PD-1 + T cells in PBL and matched TILs of CRC patients. D Statistical analysis of the frequency of CD8 + PD-1 + T cells in PBLs and matched TILs of CRC patients. E Typical results of the frequency of CD8 + CXCL13 + T cells in PBLs and matched TILs of CRC patients. F. Statistical analysis of the frequency of CD8 + CXCL13 + T cells in PBLs and matched TILs of CRC patients
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Phenotype analysis of peripheral blood lymphocytes and matched tumor infiltrating lymphocytes form CRC patients. A Typical results of flow cytometry analysis revealed the frequency of CD39 + CD103 + CD8 + T cells in PBLs and matched TILs of CRC patients. B Statistical analysis of the frequency of CD39 + CD103 + T cells in PBLs and matched TILs of CRC patients. C Typical results of the frequency of CD8 + PD-1 + T cells in PBL and matched TILs of CRC patients. D Statistical analysis of the frequency of CD8 + PD-1 + T cells in PBLs and matched TILs of CRC patients. E Typical results of the frequency of CD8 + CXCL13 + T cells in PBLs and matched TILs of CRC patients. F. Statistical analysis of the frequency of CD8 + CXCL13 + T cells in PBLs and matched TILs of CRC patients

Journal: Cancer Immunology, Immunotherapy : CII

Article Title: Identification and validation of tumor-specific T cell receptors from tumor infiltrating lymphocytes using tumor organoid co-cultures

doi: 10.1007/s00262-024-03749-8

Figure Lengend Snippet: Phenotype analysis of peripheral blood lymphocytes and matched tumor infiltrating lymphocytes form CRC patients. A Typical results of flow cytometry analysis revealed the frequency of CD39 + CD103 + CD8 + T cells in PBLs and matched TILs of CRC patients. B Statistical analysis of the frequency of CD39 + CD103 + T cells in PBLs and matched TILs of CRC patients. C Typical results of the frequency of CD8 + PD-1 + T cells in PBL and matched TILs of CRC patients. D Statistical analysis of the frequency of CD8 + PD-1 + T cells in PBLs and matched TILs of CRC patients. E Typical results of the frequency of CD8 + CXCL13 + T cells in PBLs and matched TILs of CRC patients. F. Statistical analysis of the frequency of CD8 + CXCL13 + T cells in PBLs and matched TILs of CRC patients

Article Snippet: For CD39 + CD103 + positive T cell analysis, TILs and PBLs from CRC patients were stained with anti-human CD3-FITC, anti-human CD8-PE, anti-human CD39-PE-Cy7, anti-human CD103-APC antibodies cocktails and 7AAD (Invitrogen).

Techniques: Flow Cytometry